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recombinant sars cov 2 receptor binding domain  (Sino Biological)


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    Structured Review

    Sino Biological recombinant sars cov 2 receptor binding domain
    Recombinant Sars Cov 2 Receptor Binding Domain, supplied by Sino Biological, used in various techniques. Bioz Stars score: 94/100, based on 162 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/rbd+domain/pm40408511-90-18-28?v=Sino+Biological
    Average 94 stars, based on 162 article reviews
    recombinant sars cov 2 receptor binding domain - by Bioz Stars, 2026-07
    94/100 stars

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    Sino Biological recombinant sars cov 2 receptor binding domain
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    Sino Biological rbd domain
    LRP1 expression enhances ACE2-mediated internalization of SARS CoV-2 pseudovirions. HEK293 cells stably expressing ACE2 were transfected with GFP-LRP1, and transfection was confirmed by immunoblot analysis ( A ). B – D , LRP1-transfected cells were incubated with pseudovirions containing Vesicular Stomatitis Virus (VSV) ( B ), SARS-CoV-2 <t>S-protein</t> ( C ) or Δenv pseudovirions ( D ). (Students t test; ∗ p < 0.05, ∗∗∗∗ p < 0.0001).
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    LRP1 expression enhances ACE2-mediated internalization of SARS CoV-2 pseudovirions. HEK293 cells stably expressing ACE2 were transfected with GFP-LRP1, and transfection was confirmed by immunoblot analysis ( A ). B – D , LRP1-transfected cells were incubated with pseudovirions containing Vesicular Stomatitis Virus (VSV) ( B ), SARS-CoV-2 S-protein ( C ) or Δenv pseudovirions ( D ). (Students t test; ∗ p < 0.05, ∗∗∗∗ p < 0.0001).

    Journal: The Journal of Biological Chemistry

    Article Title: The LDL receptor-related protein 1 (LRP1) facilitates ACE2-mediated endocytosis of SARS-CoV2 spike protein-containing pseudovirions

    doi: 10.1016/j.jbc.2025.110227

    Figure Lengend Snippet: LRP1 expression enhances ACE2-mediated internalization of SARS CoV-2 pseudovirions. HEK293 cells stably expressing ACE2 were transfected with GFP-LRP1, and transfection was confirmed by immunoblot analysis ( A ). B – D , LRP1-transfected cells were incubated with pseudovirions containing Vesicular Stomatitis Virus (VSV) ( B ), SARS-CoV-2 S-protein ( C ) or Δenv pseudovirions ( D ). (Students t test; ∗ p < 0.05, ∗∗∗∗ p < 0.0001).

    Article Snippet: The SARS-CoV-2 spike protein receptor binding domain (his tagged, containing residues Arg319-Phe541) was purchased from R&D systems (Catalog number 10523-CV-100).

    Techniques: Expressing, Stable Transfection, Transfection, Western Blot, Incubation, Virus